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NAD + is a crucial cofactor for both mitochondrial bioenergetics and for the above-mentioned homeostasis pathways (Fig

Nguyen B, Bix G, Yao Y

Acknowledgements This work was financially supported by the National Natural Science Foundation of China (NSFC 52322309 and 52173139), the Young Talent Support Plan of Xian Jiaotong University, and Fundamental Research Funds for the Central Universities (xzy022021040, xzy022021052, xzy012023098, and xzy012023105)